Nuclear lamina

The nuclear lamina is a dense (~30 to 100 nm thick) fibrillar network inside the nucleus of eukaryote cells. It is composed of intermediate filaments and membrane associated proteins. Besides providing mechanical support, the nuclear lamina regulates impo

由 Y Gruenbaum 著作 · 2003 · 被引用 284 次 — The nuclear lamina is an essential component of metazoan cells. It is involved in most nuclear activities including DNA replication, RNA transcription, nuclear ...

由 U Aebi 著作 · 1986 · 被引用 1191 次 — The nuclear lamina, a protein meshwork lining the nucleoplasmic surface of the inner nuclear membrane, is thought to provide a framework for organizing ...

GO:0005652 JSON. nuclear lamina. Cellular Component. Definition (GO:0005652 GONUTS page). The fibrous, electron-dense layer lying on the nucleoplasmic side ...

由 C Almendáriz-Palacios 著作 · 2020 · 被引用 16 次 — The accumulation and aggregation of intracellular phosphorylated-Tau (p-Tau), which normally functions to stabilize microtubules in its non-phosphorylated state ...

由 BE Danielsson 著作 · 2023 · 被引用 3 次 — The nuclear lamina is thought both to shield DNA from excessive mechanical forces and to transmit mechanical forces onto the DNA. However, to ...

由 RM Skory 著作 · 2023 · 被引用 11 次 — Lamin-A is mechanically coupled to the cell cortex and responds to forces driving inner-outer segregation. These changes in Lamin-A trigger ...

The nuclear lamina is a protein meshwork located at the nuclear membrane possessing a structural role, but also protecting the genetic material and regulating ...

Nuclear lamins: building blocks of nuclear architecture. (PDF). Genes ... 外部連結. 編輯 · 醫學主題詞表（MeSH）：Nuclear+Lamina · Kenny023最後編輯於1年前 ...